PhD Thesis:

“Interval and possibilistic methods for constraint-based metabolic models”

Ph.D. Francisco Llaneras | Supervisor: Prof. Jesús Picó

The thesis is devoted to the study and application of constraint-based metabolic models. The objective was to find simple ways to handle the difficulties that arise in practice due to uncertainty (knowledge is incomplete, there is a lack of measurable variables, and those available are imprecise). With this purpose, tools have been developed to model, analyse, estimate and predict the metabolic behaviour of cells.